Materials And Methods For Filling Biological Cavities And Preventing Leakage Of Injected Therapeutic Agents

Injection of biomolecules, genes and cells is commonly used in biological therapies. For example, intra-discal injection of biomolecules such as transforming growth factor-beta 1 has been used in the treatment of degenerative intervertebral discs (IVD). Recently, mesenchymal stem cell (MSC)-based therapy for treating degenerative discs has received much attention.

Medical Devices

Aptamers for the Treatment of Osteoporosis

Currently only 3 product classes available in the market. Among them, bisphonsphonate and SERMs are in the late growth phase of the product life cycle, while parathyroid hormones is in the infancy stage. All these drugs have severe side effects to the body.

Therapeutic Biologics

Anti-HER2 and Anti-IGF-IR Bi-specific Antibodies for Ovarian Cancers

IGF-1R is implicated in several cancers. Due to the similarity of the structures of IGF-1R and the insulin receptor (IR), especially in the regions of the ATP binding site and tyrosine kinase regions, synthesizing selective inhibitors of IGF-1R is difficult.

Therapeutic Biologics