Novel Antimicrobial Peptide Remineralises Tooth Surface of Dental Caries
- Field
- Medical Devices
- Reference No.
- IP00903
Background
- Dental caries: a leading public health problem worldwide
- 2.5 billion people have untreated caries which may lead to serious infection, loss of teeth, or even serious systemic health issue
- Micro-organisms accumulate on tooth surfaces easily producing local acidic environment which causes softening of teeth
- Preventing micro-organisms adhesion and restoring the decayed tooth surfaces are very important for dental hygiene
Technology Overview
- The modified peptide has DUAL BIOACTIVE properties:
- prevent adhesion of micro-organisms on tooth surface
- regenerate mineralized surface on decayed tooth with protection from demineralization of tooth surface
- The peptide can be totally synthetic and relatively stable with low toxicity
- Its production is relatively easy to control
-
Figure 1: Antibacterial function
Figure 2: Protects the demineralization of enamel surfaces
Figure 3: Promotes mineralization of enamel surface
Applications
- Additive to dental hygiene products such as toothpaste and mouthwash
- Stand alone protective gel with daily multiple applications
Patents
- US Provisional Application No. 62/950,236
- Entering PCT phase: can cover all major markets globally
IP Status
- Patent application submitted